About Hygenerate
Precision. Not Protocols.
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Systems-based care designed for physiologic restoration.
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Hygenerate is a founder-led, systems-based medical practice focused on identifying and restoring upstream drivers of dysfunction across hormonal, metabolic, immune, and stress pathways.
We serve patients locally in North Carolina and in multiple states nationwide through telehealth, where licensure permits.
Our Story
Hygenerate was founded in response to a gap in conventional medical care.
Too often, patients are told their laboratory values are “normal” while they continue to experience fatigue, metabolic shifts, hormonal disruption, inflammatory symptoms, or stress-related dysfunction. Care becomes fragmented. Symptoms are managed in isolation. The underlying pattern remains unaddressed.
We believed there was a better way.
Hygenerate was built around a structured model of pattern recognition and physiologic restoration — integrating hormonal, metabolic, immune, and stress regulation into one cohesive clinical framework.
Our goal is not temporary stimulation or short-term symptom suppression.
Our goal is measurable, sustainable physiologic balance.
We are proud to remain locally rooted while extending care to patients nationwide through telehealth.
Our Model of Care
This framework guides every clinical pathway within Hygenerate.
The body does not function in silos.
Thyroid signaling influences metabolism.
Stress physiology impacts immune response.
Insulin resistance alters reproductive hormones.
Inflammatory burden affects endocrine regulation.
For this reason, we evaluate interconnected systems rather than isolated complaints.
We prioritize:
• Comprehensive systems-based evaluation
• Precision diagnostics
• Data-guided clinical decision making
• Measurable physiologic response
• Longitudinal monitoring
Care is structured.
Care is collaborative.
Care is intentionally paced.
Our Leadership
​Julianne Tondreau, DNP, FNP-BC
Founder & Clinical Director
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Dr. Tondreau founded Hygenerate to deliver structured, physiology-driven care for patients navigating complex hormonal and metabolic dysfunction. With more than 20 years in healthcare, her work centers on regulatory balance, diagnostic precision, and sustainable long-term outcomes.
She directs all clinical strategy and provides oversight across every service line to ensure disciplined, accountable medicine at every level of care.​
Ashley Pelletier, CCMA
Director of Operations & Practice Strategy
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Ashley leads practice operations while helping shape the organizational culture and patient experience at Hygenerate. She oversees scheduling systems, workflow structure, communication standards, and operational strategy — ensuring care remains coordinated, clear, and seamless from intake through follow-up.
Her leadership supports both the clinical team and the patients they serve, reinforcing a structured and collaborative model of care.
Our Clinical Team
While leadership shapes the direction of Hygenerate, patient care is delivered by our dedicated clinical staff — licensed nurse practitioners trained in our comprehensive care model.
Each clinician practices within established care pathways and shared clinical standards to ensure continuity, safety, and depth of care.
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For Referring Providers
We value collaborative care.
Hygenerate works alongside primary care physicians and specialists within clearly defined scopes of practice to support continuity and long-term physiologic stability. We prioritize transparent communication, measurable outcomes, and appropriate co-management when indicated.